| HBV-M定量检测与HBV-DNA含量水平关系的初步探讨 |
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| 引用本文： | 王山梅,孙长义. HBV-M定量检测与HBV-DNA含量水平关系的初步探讨[J]. 河南职工医学院学报, 2002, 14(2): 129-130,132 |
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| 作者姓名： | 王山梅 孙长义 |
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| 作者单位： | 河南省人民医院检验科,郑州,450003;河南省人民医院检验科,郑州,450003 |
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| 摘 要： | 目的 研究乙型肝炎病毒标志物定量检测结果与其HBV-DNA含量的临床关系。方法 采用时间分辨免疫定量和荧光定量-PCR技术,对HBV-DNA和HBV-DNA含量进行检测。结果 在HBsAg/HBeAg/HBcAb,HBsAg/HBcAb/HBcAb,HBeAg/IC及单纯HBcAb阳性的四个组别中,HBV-DNA阳性率分别是97.17%、30.56%、100%和25%;在HBsAg,HBeAg,HBeAb,HBcAb定量检测高,低值两组HBV-DNA含量对比中,HBV-DNA阳性率分别为76.92%、58.14%;100%、97.26%;20.00%、11.42%;64.62%、27.63%。结论 HBV-DNV比HBV-M更能及时准确反映乙型肝炎病毒感染者的病程情况。
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| 关 键 词： | 乙型肝炎病毒 聚合酶链反应 DNA 免疫酶技术 |
| 文章编号： | 1008-9276(2002)02-0129-02 |
Preliminary Study on the Relationships between HBV Immunological Marker and HBV-DNA Concentrations |
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| Wang Shanmei Sun Changyi. Preliminary Study on the Relationships between HBV Immunological Marker and HBV-DNA Concentrations[J]. Journal of Henan Medical College For Staff and Workers, 2002, 14(2): 129-130,132 |
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| Authors: | Wang Shanmei Sun Changyi |
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| Abstract: | Objective To investigate the relationships between HBV infected patients immunological marker and HBV-DNA concentrations.Methods TRFIA and FQ-PCR methods were applied in the analysis of HBV immunological marker and HBV-DNA concentrations in 216 HBV infected patients.Results In patients with HBsAg+/HBeAg+/HBcAb,HBsAg+/HBeAb+/HBcAb+,HBeAg+/IC+,and HBcAb+,the HBV-DNA positive rate were 97.17%?30 56%?100%?25%.In the high and low titer groups about HBsAg+, HBeAg+, HBeAb+, and HBcAb+, the HBV-DNA positive rate were 76.92%?58 14%;100%?97 26%;20 00%?11 42%;64 62%?27 63%.Conclusion HBV-DNA is more rapid and exact than HBV immunological marker to reflect the HBV infected patients. [ |
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| Keywords: | hepatitis B virus polymerase chain reaction DNA immunoassay |
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