| 正交设计试验优选神农心脑康胶囊的制备工艺 |
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| 引用本文： | 张晓春,张振建,张长弓,王云山.正交设计试验优选神农心脑康胶囊的制备工艺[J].中国医院药学杂志,2006,26(3):256-258. |
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| 作者姓名： | 张晓春 张振建 张长弓 王云山 |
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| 作者单位： | 1. 随州市中心医院,湖北,随州,441300
2. 华中科技大学同济医学院药学院,湖北,武汉,430030 |
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| 基金项目： | 湖北省重点科技发展指导性项目(编号:991B27) |
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| 摘 要： | 目的:优选神农心脑康胶囊的最佳制备工艺。方法:对君药银杏叶、川芎的提取工艺用正交试验进行优选。结果:银杏叶、川芎粉碎成粗粉,用15倍量60%的乙醇渗漉条件最佳,总黄酮和川芎嗪的含量最高。结论:银杏叶、川芎粉碎过10目筛,用15倍60%乙醇渗漉,既经济又实用。
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| 关 键 词： | 正交试验 神农心脑康胶囊 制备工艺 |
| 文章编号： | 1001-5213(2006)03-0256-03 |
| 收稿时间： | 2004-11-08 |
| 修稿时间： | 2004年11月8日 |
Optimization of production process of Shennong Xinnaokang capsules by orthogonal design |
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| ZHANG Xiao-chun,ZHANG Zhen-jian,ZHANG Chang-gong,WANG Yun-shan.Optimization of production process of Shennong Xinnaokang capsules by orthogonal design[J].Chinese Journal of Hospital Pharmacy,2006,26(3):256-258. |
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| Authors: | ZHANG Xiao-chun ZHANG Zhen-jian ZHANG Chang-gong WANG Yun-shan |
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| Institution: | 1. Suizhou Center Hospital, ttubei Suizhou 441300,China; 2.School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Huhei Wuhan 430030, China |
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| Abstract: | OBJECTIVE To optimize the production process of Shennong Xinnao Kang capsules.METHODS To optimize the extraction process of Folium Ginkgo and Rhizoma Chuanxiong by orthogonal test.RESULTS The extraction conditions were optimized as follows:Folium Ginkgo and Rhizoma Chuanxiong were powdered and soaked by fifteenfold-weight 60% alcohol,to get the highest content of Flavone and ligustrazine.CONCLUSION The process is feasible for the preparation of the capsules. |
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| Keywords: | orthogonal design Shennong Xinnao Kang capslues production process |
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