Zur HPLC-Trennung einiger Mandelsäureesterderivate mittels α1-Glykoprotein (AGP)

HPLC-Separation of Some Mandelic Acid Ester Derivatives Using α₁-Acid Glycoprotein (AGP) Investigations on direct HPLC-resolution of the racemates of mandelic acid ester and phenylacetic acid ester derivatives using α₁-acid glycoprotein on silica (AGP) as the chiral stationary phase are described. The influence of various uncharged and charged modifiers (2-propanol, octanoic acid, N,N-dimethyloctylamine) in the mobile phase separately and in combination by variation of the pH-value was studied.