Case Study: An intraoperative finding of black bone disease in a podiatric surgery patient |
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| Institution: | 1. Diabetology Department, Centre Hopitalier Sud Francilien, Corbeil Essonnes, France;2. Diabetology Department, AP-HP, Hôpital Pitié-Salpêtrière, F-75013 Paris, France;3. Centre de recherche des Cordeliers INSERM U1138 Team “Diabetes, metabolic diseases and comorbidities”, 15 rue de l''Ecole de Médecine, 75270 Paris cedex 06, France;4. Vascular Surgery Department AP-HP, Hôpital Pitié-Salpêtrière, F-75013 Paris, France;5. Clinical Research Unit centre hospitalier sud Francilien, 40 Avenue Serge Dassault, 91100 Corbeil-Essonnes, France;6. Sorbonne Université, 15 rue de l''Ecole de Médecine, 75006 Paris, France;1. Cancer Molecular Pathology, School of Medicine, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia;2. Genomics Research Centre, Institute of Health and Biomedical Innovation, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia;3. Pathology Queensland and Gold Coast University Hospital, Gold Coast, Queensland, Australia;1. Molecular Biology and Human Genetics Laboratory, Department of Zoology, The University of Burdwan, West Bengal, India;2. Department of Biochemistry, Calcutta National Medical College, Kolkata, India;3. Department of Pathology, Burdwan Medical College and Hospital, Burdwan, India;4. Department of Pathology, Bankura Medical College and Hospital, Bankura, India;5. Department of Gynecology and Obstetrics, Burdwan Medical College and Hospital, Burdwan, India |
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| Abstract: | Black bone disease has been recognised as a potential consequence of long-term treatment with tetracycline antibiotics. Largely documented affecting structures in the head and skull, there are few reported cases of black bone disease in the foot and ankle. The case of a 55 years old patient, who as a teenager, had undergone treatment with minocycline hydrochloride for chronic acne, and was found to have bone discolouration consistent with minocycline induced black bone disease (MIBBD) during the course of hallux valgus corrective surgery some 40 years later, is presented. In spite of the intraoperative findings, the patient’s post-operative recovery and bone healing was uneventful. The literature on minocycline induced black bone disease is reviewed. |
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| Keywords: | Black bone disease Tetracyclines Minocycline hydrochloride Foot Hallux valgus Podiatric surgery |
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