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Inappropriate empirical antibiotic therapy for bloodstream infections based on discordant in-vitro susceptibilities: a retrospective cohort analysis of prevalence,predictors, and mortality risk in US hospitals
Authors:Sameer S Kadri  Yi Ling Lai  Sarah Warner  Jeffrey R Strich  Ahmed Babiker  Emily E Ricotta  Cumhur Y Demirkale  John P Dekker  Tara N Palmore  Chanu Rhee  Michael Klompas  David C Hooper  John H Powers  Arjun Srinivasan  Robert L Danner  Jennifer Adjemian
Affiliation:1. Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD, USA;2. Hospital Epidemiology Service, National Institutes of Health Clinical Center, Bethesda, MD, USA;3. Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA;4. Epidemiology Unit, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA;5. Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA;6. United States Public Health Service, Commissioned Corps, Rockville, MD, USA;7. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA;8. Brigham and Women''s Hospitals, Boston, MA, USA;9. Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA;10. Division of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA;11. Clinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA;12. Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Abstract:
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