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| 端粒维持基因多态性与膀胱癌易感性的关系(英文) | |
| 引用本文： | Chengyuan Gu,Yao Zhu,Dingwei Ye. 端粒维持基因多态性与膀胱癌易感性的关系(英文)[J]. 中德临床肿瘤学杂志, 2013, 12(9): 448-453. DOI: 10.1007/s10330-012-1208-1 |
| 作者姓名： | Chengyuan Gu Yao Zhu Dingwei Ye |
| 作者单位： | Department of Urology, Fudan University Shanghai Cancer Center;Department of Oncology, Shanghai Medical College of Fudan University |
| 摘 要： | Telomere maintenance genes play an important role in maintaining the integrity of the telomere structure that protects chromosome ends,and telomere dysfunction may lead to tumorigenesis.Genetic variation in telomere maintenance genes has been confirmed.Cumulative evidence shows that the difference of telomere length and stability among the individual depends on the genetic variants of telomere maintenance genes.Genetic variants in telomere maintenance genes may affect telomere length and stability,thus the increased cancer risk.This review intends to summarize the association of genetic variants in telomere maintenance genes with bladder cancer risk. |
| 关 键 词： | telomere maintenance genes polymorphism bladder cancer susceptibility |
Genetic variants in telomere-maintenance genes and bladder cancer risk |
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| Chengyuan Gu,Yao Zhu,Dingwei Ye. Genetic variants in telomere-maintenance genes and bladder cancer risk[J]. The Chinese-German Journal of Clinical Oncology, 2013, 12(9): 448-453. DOI: 10.1007/s10330-012-1208-1 | |
| Authors: | Chengyuan Gu Yao Zhu Dingwei Ye |
| Affiliation: | 1. Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China 2. Department of Oncology, Shanghai Medical College of Fudan University, Shanghai, 200032, China |
| Abstract: | Telomere maintenance genes play an important role in maintaining the integrity of the telomere structure that protects chromosome ends, and telomere dysfunction may lead to tumorigenesis. Genetic variation in telomere maintenance genes has been confirmed. Cumulative evidence shows that the difference of telomere length and stability among the individual depends on the genetic variants of telomere maintenance genes. Genetic variants in telomere maintenance genes may affect telomere length and stability, thus the increased cancer risk. This review intends to summarize the association of genetic variants in telomere maintenance genes with bladder cancer risk. |
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| 本文献已被 CNKI SpringerLink 等数据库收录！ | |