Poster 36: Neuropsychiatric symptoms in patients with traumatic brain injury: 2 years postdischarge

Objective: To assess the prevalence of neuropsychiatric symptoms in traumatic brain injury (TBI) 2 years postdischarge from inpatient rehabilitation and its associated caregiver distress. Design: Follow-up study. Setting: Inpatient acute rehabilitation hospital and community. Participants: 39 consecutive patients with TBI. Interventions: Not applicable. Main Outcome Measure: The Neuropsychiatric Inventory. Results: Neuropsychiatric symptoms were present in 75% of our sample 2 years postdischarge from acute rehabilitation. Among these symptoms, the most frequently encountered were: irritability, 48.7%; depression, 43.6%; appetite and eating changes, 25.6%; night-time and sleep behavior, 23.1%; apathy, 20.5%; anxiety, 17.9%; agitation and aggression, 17.9%; and disinhibition, 10.3%. The least frequently observed behaviors included: hallucinations, 5.1%; euphoria and elation, 2.6%; and delusions, 0%. At 2-year follow-up, anxiety, agitation and aggression, apathy, and irritability caused the most emotional distress to the caregivers, while hallucination and euphoria caused the least. Conclusions: Neuropsychiatric symptoms are prevalent in patients with TBI after discharge from acute rehabilitation. These symptoms are associated with significant caregiver distress. These findings further support the continued need for adequate psychologic assessment and possible intervention postdischarge.