烧伤创面的细菌分离及其耐药性的初步分析

目的 适时了解烧伤病房的细菌分布及耐药情况,为临床有针对性地选择和合理使用抗生素提供依据.方法 分离7个月份的烧伤患者创面细菌,并对其主要的感染菌种进行耐药性分析.结果 从烧伤患者创面共分离到细菌204株,前三位依次为金黄色葡萄球菌(87株)、铜绿假单胞菌(44株)和奇异变形杆菌(43株).金黄色葡萄球菌对万古霉素(V...

Isolation of Bacterial Strains from Burned Wounds Flora and Preliminary Analysis of Their Drug Resistance

Objective To explore the distribution and drug-resistance situation of the bacteria in the burn ward, and supply reference for scientific selection and reasonable utilization of antibiotics in clinic. Methods Bacteria from the burn wounds flora in 7 months were isolated, and the drug resistance of the main bacteria were analysed. Results Totally 204 strains of bacteria were obtained. The first three bacteria were S. aureus （87 strains）, P. aeruginosa （44 strains） and P. mirabilis （43 strains）. Isolated S. aureus were completely susceptible to vacomycin, susceptible to Quinupristin and Nitrofurantoin, but resistant to other antibioics. 91.7% of them were verified to be methicillin-resistant staphylococcus aureus（MRSA）. Isolated P. aeruginosa had different resistance rate （40%-93%） to 14 antibiotics. Isolated P. mirabilis were completely susceptible to MEM, IMP and OFX, and completely resistant to SXT. Conclusion Isolated S. aureus and P. aeruginosa are resistant to most antibiotics, isolated P. mirabilis are relatively susceptible, but the positive rate of extended-spectrun β-lectamases（ESBLs） strains is above 80%.