| 不同器官保存液对大鼠胸腺移植物的影响 |
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| 引用本文： | 孙大强,王胜发,王巨,禹亮,李野. 不同器官保存液对大鼠胸腺移植物的影响[J]. 基础医学与临床, 2005, 25(10): 953-956 |
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| 作者姓名： | 孙大强 王胜发 王巨 禹亮 李野 |
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| 作者单位： | 哈尔滨医科大学,第一医院,胸外科,黑龙江,哈尔滨,150001;哈尔滨医科大学,第一医院,胸外科,黑龙江,哈尔滨,150001;哈尔滨医科大学,第一医院,胸外科,黑龙江,哈尔滨,150001;哈尔滨医科大学,第一医院,胸外科,黑龙江,哈尔滨,150001;哈尔滨医科大学,第一医院,胸外科,黑龙江,哈尔滨,150001 |
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| 基金项目： | 黑龙江省科委重点攻关课题（G97C180402） |
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| 摘 要： | 目的评价不同保存液对大鼠胸腺移植物的影响。方法分别将大鼠胸腺用乳酸林格液、UW液、HTK液保存后进行异体移植，观察其超微结构的变化并检测ATP、SOD、MDA含量。结果与乳酸林格液相比，UW液、HTK液所保存的大鼠胸腺移植后，其超微结构改变小，ATP、SOD含量多，MDA含量少；HTK液保存的胸腺ATP含量显著高于UW液（P〈0．05）。结论UW液和HTK液有利于移植胸腺的保存，其中HTK液更有利于大鼠移植胸腺中ATP的贮存。
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| 关 键 词： | 保存液 胸腺移植 三磷酸腺苷 超氧化物岐化酶 丙二醛 |
| 文章编号： | 1001-6325(2005)10-0953-04 |
| 收稿时间： | 2004-05-31 |
| 修稿时间： | 2005-03-14 |
Effect of different preservation solutions on thymus grafts in rats |
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| SUN Da-qiang,WANG Sheng-fa,WAN Ju,YU Liang,LI Yie. Effect of different preservation solutions on thymus grafts in rats[J]. Basic Medical Sciences and Clinics, 2005, 25(10): 953-956 |
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| Authors: | SUN Da-qiang WANG Sheng-fa WAN Ju YU Liang LI Yie |
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| Affiliation: | Department of Thoracic Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China |
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| Abstract: | Objective To evaluate the effects of different preservation solutions on thymus grafts in rats, rat thymus grafts were transplanted after being preserved with Ringer lactate solution, UW solution or HTK solution. Methods The contents of ATP, SOD and MDA in thymus grafts were measured and the uhrastructures were observed. Results Compared with Ringer lactate solution, the contents of ATP and SOD in thymus preserved with UW solution and HTK solution were higher but the content of MDA was less, the uhrastructure of thymus was less damaged. The content of ATP was mostly kept in thymus with UW solution. Conclusion All data showed that UW solution and eservation of thymus and HTK solution should be more favorable for storing of ATP in HTK solution could facilite the prthymus. |
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| Keywords: | preservation solution thymus transplantation ATP SOD MDA |
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