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The association between availability of serotonin transporters and time to relapse in heroin users - A two-isotope SPECT small sample pilot study |
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| Authors: | Lin Shih-Hsien Chen Kao Chin Lee Sheng-Yu Yao Wei Jen Chiu Nan-Tsing Lee I Hui Chen Po See Yeh Tzung Lieh Liao Mei-Hsiu Lu Ru-Band Yang Yen Kuang |
| Affiliation: | Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Addiction Research Center, National Cheng Kung University, Tainan, Taiwan. |
| Abstract: | Neuroimaging evidence supporting an association between either dopamine or serotonin and time to relapse of heroin users is limited. In this two-isotope SPECT small sample (N=9) pilot study, the relationship between the availability of serotonin transporter (SERT) and dopamine transporter (DAT) and the relapse of heroin users was investigated. A significant negative association between SERT availability and time to relapse among those who relapsed (N=7) was found. |
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