血清铁蛋白及CAl9-9、CA242和CEA联合检测对胰腺癌的诊断价值

目的探讨血清铁蛋白（sF）及糖类抗原19-9（CAl9-9）、糖类抗原242（CA242）和癌胚抗原（CEA）在胰腺癌患者中的阳性率的区别。方法选取2009年至2010年住院确诊胰腺癌患者61例，收集他们血清铁蛋白、cAl9-9、CA242和CEA的检测结果，并比较它们在胰腺癌的阳性率。结果胰腺癌患者血清CA242的阳性率最高达76．9％，血清铁蛋白、CAl9-9和CEA的阳性率分别是74．4％、56％和51．3％。将铁蛋白、CA242和CAl9-9联合检测后，阳性率提高至86．5％。结论血清铁蛋白、CA242、CAl9-9和CEA联合检测在胰腺癌诊断中阳性率有较大提高，可以用于胰腺癌诊断。

Value of combined detection of serum ferritin,CA19-9 ,CA242 and CEA in diagnosing pancreatic cancer

Objective To study the differences among positive rates of serum ferritin（SF） ,carbohydrate anti- gen 19-9（CA19-9）,carbohydrate antigen 242（CA242） and carcinoembryonic antigen（CEA） in the patients with pan- creatic cancer. Methods 61 inpatients with pancreatic cancer in our hospital from 2009 to 2010 were selected. The test results of serum ferritin,CAlg-9,CA242 and CEA in these inpatients were collected and their positive rates in pancreatic cancer were compared. Results Serum CA242 positive rate in the patients with pancreatic cancer was up to 76.9%. The positive rates of serum ferritin,CA19-9 and CEA were 74.4%, 56%and 51.3 % respectively. When serum ferritin,CA242 and CA19-9 were detected together,the positive rate was increased to 86.5%. Conclusion The combination detection of serum ferritin,CA242,CA19-9 and CEA significantly increase the diagnosis positive rate of pancreatic cancer, which can be used for diagnosing pancreatic cancer.