小剂量红霉素治疗早产儿喂养不耐受疗效观察

目的观察小剂量红霉素对早产儿喂养不耐受的疗效。方法将225例喂养不耐受的早产儿，随机分为两组：对照组给予保温、部分静脉营养、体位疗法等综合治疗；干预组在综合治疗基础上加用红霉素2～8mg／（kg·d），缓慢静脉滴注。结果干预组在达到全胃肠营养的时间明显比对照组缩短，差异有显著性（P〈0.01）。结论小剂量红霉素能提高早产儿喂养耐受性。

Observation on therapeutic effect of erythromycin in small dose on immature babies with feeding intolerance

Objective To observe therapeutic effect of erythromycin in small dose on immature babies with feeding intolerance. Methods 225 immature babies with feeding intolerance were randomly divided into two groups： the control group accepted the comprehensivetherapy such as keeping warm, partial parenteral nutrition, positional therapy and so on; and the treatment group, who were dripped slowly with erythromycin 2 ～ 8 mg/（ kg·d）, besides comprehensive therapy. Results In the intervention group achieved total parenteral nutrition time was shorter than the control group,the difference of two groups has significant meaning（ P 〈 0.01 ）. Conclusion The erythromycin in small dose can improve the feeding tolerance of immature babies.