依托芬那酯凝胶治疗运动系统慢性软组织损伤的临床疗效分析

目的分析依托芬那酯凝胶治疗运动系统慢性软组织损伤的有效性。方法将2011年9月-2012年3月收治的120例慢性运动系统软组织损伤患者随机分为两组,每组各60例。治疗组采用依托芬那酯凝胶予以治疗,对照组应用双氯芬酸钠乳胶剂治疗,疗程均为2周。结果治疗2周后,两组患者疼痛视觉模拟评分（VAS）≤3分者明显增加,临床疗效明显;尽管治疗组VAS评分≤3分的例数多于对照组,但两组治疗总体疗效比较,差异无统计学意义（P〉0．05）,提示两种药物对运动系统慢性损伤的疗效相当。治疗组发生不良反应2例,对照组发生不良反应3例,均较轻微,无严重不良事件发生。结论依托芬那酯凝胶治疗运动系统慢性损伤有效,元严重不良反应,特别适合有胃肠系统疾病的门诊患者。

Analysis of the Clinical Efficacy of Etofenamate Gel in Patients with Chronic Trauma of Locomotion System

Objective To analyze the clinical efficacy of etofenamate gel in patients with chronic trauma of locomotion system. Methods Randomized parallel-controlled trial was conducted. From September 2011 to March 2012, 120 patients who were diagnosed with chronic trauma of locomotion system were divided into two groups. One was etofenamate gel group （group A）, and the other was dielofenae sodium cream group （group B）. Treatment course was two weeks. Results After two weeks of therapy, the effective rate of etofenamate gel was 85.0%, and of diclofenac sodium cream was 83.3%. The difference between etofenamate gel and diclofenac sodium cream had no statistical significance. Two drugs had similar efficacy in treating chronic trauma of locomotion system. Two patients in the etofenamate gel group and three in the diclofenac sodium cream group had very slight adverse reactions. Conclusions Etofenamate gel is effective in patients with chronic trauma of locomotion system, and the efficacy is similar with diclofenac sodium cream. It is particularly suitable for patients with gastrointestinal diseases.