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The Dilemma of Target Delineation with PET/CT in Radiotherapy Planning for Malignant Tumors
引用本文:Suyu Zhu Bingqlang Hu. The Dilemma of Target Delineation with PET/CT in Radiotherapy Planning for Malignant Tumors[J]. 中国肿瘤临床(英文版), 2007, 4(6): 428-432. DOI: 10.1007/s11805-007-0428-6
作者姓名:Suyu Zhu Bingqlang Hu
作者单位:Suyu Zhu Bingqiang Hu Department of Radiation Oncology,the HuNan Province Cancer Hospital,Changsha 410013,China.
摘    要:
Currently there are many unanswered questions concerning contouring a target with PET/CT in radiotherapy planning.Who should contour the PET volume-the radiation oncologist or the nuclear medicine physician?Which factors will contribute to the dual-observer variability between them?What should be taken as the optimal SUV threshold to demarcate a malignant tumor from the normal tissue?When the PET volume does not coincide with the local area CT findings,which portion should be contoured as the target?If a reginal lymph node draining area or a remote region is shown to be PET positive but CT negative,or PET negative but CT positive,how is the target identified and selected?Further studies concerning the relationship between PET/CT and the cancerous tissue are needed.The long-term clinical results showing an increased therapeutic ratio wil finaly verify the applicability of guidelines to contour the target with PET/CT in radiotherapy planning.

关 键 词:恶性肿瘤 放射治疗 诊断 临床表现
收稿时间:2007-08-04
修稿时间:2007-08-07

The dilemma of target delineation with PET/CT in radiotherapy planning for malignant tumors
Suyu Zhu,Bingqiang Hu. The dilemma of target delineation with PET/CT in radiotherapy planning for malignant tumors[J]. Chinese Journal of Clinical Oncology, 2007, 4(6): 428-432. DOI: 10.1007/s11805-007-0428-6
Authors:Suyu Zhu  Bingqiang Hu
Affiliation:Department of Radiation Oncology, the HuNan Province Cancer Hospital, Changsha 410013, China.
Abstract:
Currently there are many unanswered questions concerning contouring a target with PET/CT in radiotherapy planning.Who should contour the PET volume-the radiation oncologist or the nuclear medicine physician?Which factors will contribute to the dual-observer variability between them?What should be taken as the optimal SUV threshold to demarcate a malignant tumor from the normal tissue?When the PET volume does not coincide with the local area CT findings,which portion should be contoured as the target?If a reginal lymph node draining area or a remote region is shown to be PET positive but CT negative,or PET negative but CT positive,how is the target identified and selected?Further studies concerning the relationship between PET/CT and the cancerous tissue are needed.The long-term clinical results showing an increased therapeutic ratio wil finaly verify the applicability of guidelines to contour the target with PET/CT in radiotherapy planning.
Keywords:PET/CT  radiotherapy planning  target delineation.
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