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曼氏血吸虫与日本血吸虫交叉免疫原性的血清学实验研究
引用本文:李允鹤,胡永德,杨光堡,殷水龙,吴宗泉,骆伟.曼氏血吸虫与日本血吸虫交叉免疫原性的血清学实验研究[J].华中科技大学学报(医学版),1986(1).
作者姓名:李允鹤  胡永德  杨光堡  殷水龙  吴宗泉  骆伟
作者单位:苏州医学院寄生虫学教研室 (李允鹤,胡永德,杨光堡,殷水龙,吴宗泉),苏州医学院寄生虫学教研室(骆伟)
基金项目:联合国开发计划署,世界银行,世界卫生组织热带病研究培训特别规划的部分物质支持
摘    要:以曼氏血吸虫的虫卵和成虫免疫家兔后所产生的特异性抗体,可用以日本血吸虫虫卵、尾蚴和成虫为抗原分别进行的COP,CHR和ELACIEP测出,表明两种人体血吸虫存有显著的交叉抗原成分。应用此种血清交叉反应性,以检测抗异种人体血吸虫的抗体,似有效而可取的,可用以辅助诊断援外回国人员是否感染国外人体血吸虫病。

关 键 词:曼氏血吸虫  日本血吸虫  血吸虫病兔疫

Serological Studies on the Cross-Immunogenicities Between Schistosoma Mansoni and Schistosoma Japonicum
Li Yunhe,Hu Yongde,Yang Guangbao,Yin Shuilong,Wu Zongquan,Luo Wei.Serological Studies on the Cross-Immunogenicities Between Schistosoma Mansoni and Schistosoma Japonicum[J].Journal of Huazhong University of Science and Technology(Health Sciences),1986(1).
Authors:Li Yunhe  Hu Yongde  Yang Guangbao  Yin Shuilong  Wu Zongquan  Luo Wei
Institution:Li Yunhe,Hu Yongde,Yang Guangbao,Yin Shuilong,Wu Zongquan,Luo Wei Department of Parasitology,Suzhou Medical College,Jiangsu
Abstract:This paper deals with the detection of specific antibodies in sera from rabbits immunized with Schistosoma mansoni egg and adult worm antigens using circumoval precipitate reaction(COP),Cercarien Hiillen Reaktion(CHR) and enzyme-linked antigen counterimmunoelectrophoresis (ELACIEP) respectively with eggs,cercariae and adult worms of Schistosoma japonicum as antigens.The results showed remarkable cross-reaction between Schistosoma mansoni and Schistosoma japonicum suggesting the existence of common antigerdc components in these two species.It is considered that the detection of the serological cross-reactivities of heterogeneous antibodies in sera from the patients with human schistosomiasis might be efficacious and feasible in the auxiliary diagnosis of schistosomiasis.(Materials were supported partially from UNDP/World Bank/WHO/TDR)
Keywords:Schistosoma japonicum  Schistosoma mansoni  immunology of schistosomiasis  
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