胼胝体梗死临床分析(附22例病例)

目的探讨胼胝体梗死的高危因素、临床表现以及影像学特点。方法对22例胼胝体梗死患者的临床资料进行回顾性分析。结果该病60～70岁为高发年龄,病因及高危因素主要为高血压病、颈动脉斑块及糖尿病。最主要的临床表现为肌力减退、失语、感觉障碍、智能障碍、小便失禁、共济失调、意识障碍等症状。胼胝体梗死部位以体部、膝部多见,常累及基底节区、额叶、顶叶、颞叶等部位。结论胼胝体梗死因其累及部位不同临床表现不同,其中颈动脉斑块为胼胝体梗死不容忽视的重要高危因素,头颅MRI对胼胝体梗死及累及部位的定位诊断有指导作用。

Clinical analysis of the corpus callosum infarction (a report of 22 cases)

Objective To study the risk factor, clinical manifestations and head MRI feature of corpus callosal infarction. Methods Retrospective analysis was undertaken in 22 cases with corpus callosal infarction, hospitalized from June 2004 to June 2005. Results The corpus callosal infarction had a high incidence rate at the age of 60~70 years, its etiology and risk factor including hypertension, diabetes mellitus, carotid atherosclerosis and its major clinical manifestations consisting of decreased muscle strength, aphasia, sensory disturbance, disturbance of intelligence, ataxia and loss of consciousness. The lesions were located mainly in the genu and splenium of corpus callosum, always involving basal ganglia, frontal lobe, parietal lobe and temporal lobe. Conclusion The clinical manifestations of corpus callosal infarction vary with lesion sites involved. Carotid atherosclerosis is one of the substantially important risk factors, and head MRI is helpful to the clinical location and treatment of corpus callosal infarction.