益气活血中药治疗放射性肺损伤临床疗效观察

目的 观察益气活血中药治疗放射性肺损伤的临床疗效。方法 在我院接受三维适形放疗的84例患者,随机分为治疗组44例和对照组40例。治疗组患者给予益气活血中药干预;对照组患者给予抗生素及激素等相应药物治疗。结果 2个月后治疗组治疗效果明显优于对照组,总有效率分别为88.6％ (39/44)和60.0％(24/40),差异有统计学意义(x2=9.16,P＜0.05)。治疗6个月后治疗组胸部CT特征与对照组比较,差异有统计学意义(x2=12.22,P＜0.05)。结论 益气活血中药对放射性肺损伤有良好的治疗作用,对放射性肺纤维化有较好的预防作用。

The clinical effects of traditional Chinese medicine which supplements Qi and activates blood circulation on the X-ray radiotherapy-induced lung injury

Objective To observe the effects of traditional Chinese medicine which supplements Qi and activates blood circulation on the treatment of the X-ray radiotherapy-induced lung injury.Methods Eighty-four patients who were given three-dimensional conformal radiotherapy were randomized into treatment group and control group.The patients in treatment group were given traditional Chinese medicine, which supplements Qi and activates blood circulation, while the patients in control group were given antibiotics and hormone instead.Results The outcome of treatment group was better than that of control.The response rates were 88.6％ and 60.0％, respectively (x2 = 9.16, P ＜ 0.05) .Compared with the patients in control group, the clinical manifestations and pulmonary CT reflected better response in the patients of the treatment group(x2 =12.22,P ＜ 0.05) .Conclusion The traditional Chinese medicine, which supplements Qi and activates blood circulation,has a good therapeutical effect on radiation pneumonitis and protective role for radiation-induced pulmonary fibrosis.