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| 胃癌高危人群脂质过氧化物、前列腺素E2的检测在预防中的意义 | |
| 引用本文： | 刘俊,温文. 胃癌高危人群脂质过氧化物、前列腺素E2的检测在预防中的意义[J]. 江西医学院学报, 1995, 35(4): 78-82 |
| 作者姓名： | 刘俊 温文 |
| 摘 要： | 检测１０２例胃疾患患者血浆、胃液中的脂质过氧化物（ＬＰＯ）和前列腺素Ｅ＿２（ＰＧＥ＿２）的含量，以研究慢性萎缩性胃炎，肠上皮化生与胃癌的关系。结果：萎缩性胃炎（３４例）与胃癌（３４例）血浆中ＬＰＯ含量无显著性差异（Ｐ＞０．０５），表明胃癌和萎缩性胃炎关系密切；血浆、胃液中ＰＧＥ＿２的含量胃癌与萎缩性胃炎，浅表性胃炎均有显著或极显著性差别（Ｐ值分别＜０．０５，＜０．０５；＜０．０１，＜０．０１）。同时发现随胃炎程度的加重，ＰＬＯ、ＰＧＥ＿２的含量逐渐升高。并对其在临床和预防中的作用进行了探讨。 |
| 关 键 词： | 过氧化脂质类 前列腺素E类 胃肿瘤 预防 放射免疫法 八木国夫法 |
The Significance of Determinaion of Lipid Peroxide and Prostaglandin E_2 Levels in High-Risk Population of Gastric Cancer |
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| Liu Jun, Wen Wen. The Significance of Determinaion of Lipid Peroxide and Prostaglandin E_2 Levels in High-Risk Population of Gastric Cancer[J]. Acta Academiae Medicinae Jiangxi, 1995, 35(4): 78-82 | |
| Authors: | Liu Jun Wen Wen |
| Affiliation: | First Affiliated Hospital .Jiangxi Medical College Nanchang 330006 |
| Abstract: | In order to study the relationship of Chronic atrophic gastritis(CAG)andintestinalmetaplasia to gastric cancer, lipid peroxide(LPO ) and prostaglandin E_2(PGE_2)levels ofplasma and gastric juice were determined in 102 patients with gastric disease. The resultsshowed that the mean level of plasma and gastric juice PGE_2 of gastric cancer patients wasmuch higher than that of CAG and CSG(P<0.5, <0.5; <0. 01,<0. 01 ).There was a closerelationship between the severity of chronic gastritis and level of LPO and PGE_2.The sever-er the chronic gastritis, the higher the LPO and PGE levels.The significance of that detec-tion of LPO and PGE_2 levels in the treatment and protectiog of chronic gastritis has been di-cussed. |
| Keywords: | high-risk populations lipid peroxides prostaglandins E stomach neoplasms/prevention & control Dept.of Pathology complement word |
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