The role of the pituitary hormones in hyperplasia of the mammary glands

Summary Combined administration of estrogens and prolactin did not induce any hyperplasia of the mammary glands of female suckling rats. However, combined administration of estrogens and gonadotropic hormones regularly caused a marked hyperplasia of the mammary glands. The extent of hyperplasia was connected with the amount of follicle-stimulating hormone administered, but did not depend upon the dose of the luteinizing hormone given; this points to the decisive role played by the follicle-stimulating hormone in the mammary gland hyperplasia occurring in female suckling rats.(Presented by Active Member AMN SSSR L. M. Shabad) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 55, No. 1, pp. 104–107, January 1963