| 疏肝健脾益肾汤联合化疗对晚期肝郁脾虚型乳腺癌患者血清炎性因子及肿瘤标志物的影响 |
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| 引用本文： | 李淑艳,黎芳. 疏肝健脾益肾汤联合化疗对晚期肝郁脾虚型乳腺癌患者血清炎性因子及肿瘤标志物的影响[J]. 肿瘤药学, 2022, 12(6): 779-784 |
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| 作者姓名： | 李淑艳 黎芳 |
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| 作者单位： | 1.烟台市烟台山医院 乳腺外科，山东 烟台，264001;2.深圳市中医院 乳甲外科，广东 深圳，518033 |
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| 摘 要： | 目的 探讨疏肝健脾益肾汤联合化疗对晚期肝郁脾虚型乳腺癌患者血清炎性因子及肿瘤标志物的影响。方法 选择2017年7月—2018年6月烟台市烟台山医院收治的晚期肝郁脾虚型乳腺癌患者120例为研究对象，采用随机数字表法分为观察组62例、对照组58例。对照组采用GP方案(吉西他滨+顺铂)化疗，观察组在对照组的基础上联合疏肝健脾益肾汤，两组均治疗18周。比较两组患者中医症状临床疗效、实体瘤临床疗效、血清炎性因子、肿瘤标志物、毒副反应等指标。结果 治疗后，观察组中医证候积分(8.43±1.35)显著低于对照组(12.52±2.45)(P<0.05)，有效率(82.86%)明显高于对照组(60.34%)(P<0.05)，缓解率(58.06%)明显高于对照组(39.66%)(P<0.05)；观察组血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)水平均显著低于对照组[(28.32±4.34)μg·L-1 vs.(35.45±5.12)μg·L-1、(76.45±9.21) pg·L-1<...
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| 关 键 词： | 晚期肝郁脾虚型乳腺癌 疏肝健脾益肾汤 化疗 炎性因子 肿瘤标志物 |
Effects of Shugan Jianpi Yishen decoction combined with chemotherapy on serum inflammatory factors and tumor markers of advanced breast cancer patients with liver stagnation and spleen deficiency |
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| LI Shuyan,LI Fang. Effects of Shugan Jianpi Yishen decoction combined with chemotherapy on serum inflammatory factors and tumor markers of advanced breast cancer patients with liver stagnation and spleen deficiency[J]. Anti-Tumor Pharmacy, 2022, 12(6): 779-784 |
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| Authors: | LI Shuyan LI Fang |
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| Affiliation: | 1.Department of Breast Surgery, Yantaishan Hospital, Yantai, 264001, Shandong, China;2.Department of Breast Surgery, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, 518033,Guangdong, China |
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| Abstract: | |
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| Keywords: | Advanced breast cancer with liver stagnation and spleen deficiency Shugan Jianpi Yishen decoction Chemotherapy Inflammatory factors Tumor markers |
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