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大鼠大脑中动脉的衰老性变化
引用本文:文灿,朱星红. 大鼠大脑中动脉的衰老性变化[J]. 解剖学杂志, 2004, 27(5): 528-530,567
作者姓名:文灿  朱星红
作者单位:第三军医大学外科应用解剖与手术学教研室,重庆,400038;第三军医大学解剖学教研室
摘    要:目的:观测大鼠大脑中动脉的衰老性变化。方法:在常规光镜、透射电镜下观察,并应用图像分析系统作测量。结果:衰老后,大鼠大脑中动脉管壁厚度几乎无改变,管腔增大;平滑肌细长,内弹性膜变薄、断裂、分层及脂质沉积。结论:高龄大鼠大脑中动脉管壁的形态和超微结构都具有显著的衰老性改变。

关 键 词:大脑中动脉  衰老  大鼠

Aging changes of middle cerebral artery in rats
WEN Can,ZHU Xing-Hong. Aging changes of middle cerebral artery in rats[J]. Chinese Journal of Anatomy, 2004, 27(5): 528-530,567
Authors:WEN Can  ZHU Xing-Hong
Abstract:Objective: To study the aging changes of the middle cerebral artery in rats. Methods:Light microscope, electron microscope and image analysis system were used.Results:In aged group, the main result observed was a significant increase in middle cerebral arterial lumen size, but the arterial wall thickness had no obvious changes. The smooth muscle cell got slender, the internal elastic laminae became thinner, delaminated and disrupted, and the lipid deposited . Conclusion:Both shape and ultrastructure are changed remarkablely in middle cerebral artery of aged rats.
Keywords:middle cerebral artery  aged  rat
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