慢性心力衰竭患者血清铁蛋白的测定及其临床意义

目的：探讨慢性心力衰竭患血清铁蛋白的变化及其临床意义。方法：采用放射免疫法测定110例慢性心力衰竭患血清铁蛋白（SF）水平，并与25例健康组相对照。结果：慢性心力衰竭患SF显高于对照组（P＜0．05），其中合并感染组显高于无感染组（P＜0．01），合并心脏恶液质综合征显低于无该合并症，随心力衰竭的加重，I，II，Ⅲ度心力衰竭组间SF依次显递减（P＜0．01）。结论：对慢性心力衰竭患进行SF的监测，有助于对疾病严重程度和预后的判断。

A study on the serum ferroprotein levels and its clinical significance in chronic heart failure

Objective: To study tle changes of the serum ferroprotein (SF) levels in patients with chronic heart failure (CHF), and its clinical significance. Methods: The SF levels were determined by radioimmunoassay in 110 patients with CHF an d 25 healthy individual (control). Results: The mean serum SF level in patients with CHF (290. 68±23. 20 mg/L) significantly heighten than in control group (190. 60± 15. 69mg/L) (P＜0.05). The differences of mean SF levels were significant among different degrees ( Ⅰ 、 Ⅱ 、 Ⅲ degree) (P＜0.01). In infected CHF patients, the mean level of the SF significantly heighten than in no-infected CHF patients (P＜0.01), and the mean level of the SF in CHF patients with syndrome of cardiac cachexia, was significantly lower than in patients without syndrome of cardiac cachexia. Conclusion: Determined the levels of the SF may be aided to estimated the severity and prognosis of the CHF.