和胃降逆法对反流性食管炎患者24h食管pH的影响*

[目的] 观察应用和胃降逆法治疗反流性食管炎,24h食管pH监测的变化情况.[方法] 将60例反流性食管炎(RE)患者随机分为对照组(30例)和治疗组(30例),对照组给予西医治疗,治疗组给予中医和胃降逆法治疗,分别观察两组治疗前后24 h食管pH监测的变化情况.[结果] 在减低食管黏膜24h pH＜4总次数、pH＜4总时间、pH＜4百分时间以及Demeester积分等方面,西医治疗与中医和胃降逆法对于反流性食管炎患者的作用相当;中医和胃降逆法对于食管黏膜24 h最长反流持续时间的减低较西医治疗更为显著,西医治疗对于反流时间持续≥5 min次数的减低较中医和胃降逆法更为显著.[结论] 和胃降逆法能够有效降低食管pH值,治疗反流性食管炎疗效确切.

Influence of Hewei Jiangni method on 24-hour esophageal pH value in reflux esophagitis

[Objective] To observe influence on change of 24-hour esophageal pH value in reflux esophagitis (RE) treated by Hewei Jiangni Method.[Methods] 60 RE patients were divided into control group (30 cases) and treatment group (30 cases),control group was treated by west medicine,treatment group was treated by Hewei Jiangni,and observing the change of 24-hour esophageal pH Value separately in two groups.[Results] Hewei Jiangni method of Tridational Chinese Medicine (TCM) and west medicine had the same influence on reducing the times of pH<4,whole time of pH<4,time% of pH<4 and Demeester in 24-hour,the influence on reducing the longest refux time in 24-hour by west medicine was not stronger than Hewei Jinagni method,the influence on reducing the times of refux continuance time,Smin by Hewei Jiangni method was not stronger than west medicine.[Conclusion] Hewei Jiangni method could reduce the 24-hour esophageal pH value effectively,and the therapeutic efficacy in treating RE was affirmed.