厦门地区1982对生殖异常夫妇染色体分析

目的对生殖异常夫妇进行染色体分析,探讨染色体异常与生殖异常的关系。方法对1982对生殖异常夫妇的外周血淋巴细胞培养,G显带进行染色体核型分析。结果染色体异常占受检人数的9.66%(383/3964)。其中不孕不育的夫妇,染色体异常占受检人数的11.27%(224/1988);流产死胎、胚胎停育的夫妇,染色体异常占受检人数的9.02%(140/1552);生育畸形儿或智低儿的夫妇,染色体异常占受检人数的4.48%(19/424)。结论生殖异常与染色体异常密切相关,对生殖异常夫妇进行染色体核型分析可以寻找病因,指导优生优育,因此是非常必要的。

Chromasomalanalysis for 1982 couples with reproductive abnormality in Xiamen area

Objective： Carry on the chromosome analysis to the reproductive abnormality couples, to study the relationship between chromosome exceptionally and reproduction abnormality. Methods： Gathers the 1982 couples＇ peripheral blood to carry on cultivating, to make chromosome G - banding and karyotype analysis. Results ： Chromosomal abnormalities accounted for 9.66 percent the number of subjects （383/3964） . One of the couples infertility, chromosomal abnormalities account for 11.27% of samples （224/ 1988） ; abortion stillbirth, infertility and his wife stopped embryos, the number of chromosomal abnormalities of subjects accounted for 9. 02% （140/1552） ; birth deformities abuse or low infant Moses and his wife, found the number of chromosomal abnormalities accounted for 4.48% （19/424） . Conclusion： Reproductive anomalies and chromosomal abnormalities was closely related to couples of reproductive abnormalities Cytogenetic examination could find the cause, the guidance of birth, it was very necessary.