Personal experience with the procurement of 132 liver allografts |
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Authors: | K Yanaga A G Tzakis T E Starzl |
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Institution: | (1) Department of Surgery, University Health Science Center of Pittsburgh, University of Pittsburgh, Falk Clinic 4 West, 3601 Fifth Avenue, 15213 Pittsburgh, PA, USA;(2) The Veterans Administration Medical Center, University Drive C, 15213 Pittsburgh, PA, USA |
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Abstract: | A single donor surgeon's experience procuring the livers from 132 donors is described. Thirty-seven grafts (28.9%) had hepatic
arterial anomalies, 19 (14.4%) of which required arterial reconstruction prior to transplantation. Of the 121 grafts evaluated
for early function, 103 grafts (85.2%) functioned well, whereas 14 grafts (11.6%) functioned poorly and 4 grafts (3.3%) failed
to function at all. The variables associated with less than optimal function of the graft consisted of donor age (P<0.05), duration of donor's stay in the intensive care unit (P<0.005), abnormal graft appearance (P<0.05), and such recipient problems as vascular thromboses during or immediately following transplantation (P<0.005). A new preservation fluid, University of Wisconsin solution, allowed safe and longer cold storage of the liver allograft
than did Euro-Collins' solution (P<0.0001). A parameter of liver allograft viability, which is simple and predictive of allograft function prior to the actual
transplant procedure, is urgently needed. |
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Keywords: | Liver transplantation procurement Procurement of the liver Arterial anomalies and liver procurement |
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