姜黄素对A549裸鼠移植瘤影响的网状Meta分析 |
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引用本文: | 杨佳卉,张雅婷,唐佳,沈克非,王万聪,陈卿斌,黄鹏,田金徽. 姜黄素对A549裸鼠移植瘤影响的网状Meta分析[J]. 中国药物评价, 2016, 33(4): 197-200 |
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作者姓名: | 杨佳卉 张雅婷 唐佳 沈克非 王万聪 陈卿斌 黄鹏 田金徽 |
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作者单位: | 兰州大学循证医学中心,兰州大学基础医学院,,,,,,, |
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基金项目: | ]甘肃省循证医学与临床转化重点实验室开放基金;兰州大学中央高校基本科研业务专项资金资助(lzujbky-2015-170;lzujbky-2014-18) |
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摘 要: | 目的:评价姜黄素对A549裸鼠移植瘤影响。方法:系统检索主要中文数据库,纳入数据库中有关姜黄素对A549裸鼠移植瘤影响的动物实验,采用SYRCLE动物实验风险评估工具评价纳入研究质量,STATA13.0软件对数据进行合并分析。结果:共纳入7个研究,网状Meta分析结果显示,与空白相比姜黄素能够减轻瘤重,缩小肿瘤体积,降低肿瘤微血管密度,在姜黄素基础上,加用顺铂可以增加疗效。结论:姜黄素对A549肺癌细胞裸鼠移植瘤的生长具有明显抑制作用。
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关 键 词: | 姜黄素 A549 网状Meta分析 |
收稿时间: | 2016-07-17 |
修稿时间: | 2016-07-17 |
Network Meta-analysis of the effects of Curcumin on human lung adenocarcinoma A549 xenografted tumor in nude mice |
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Affiliation: | Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Gansu Lanzhou,Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Gansu Lanzhou,Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Gansu Lanzhou,Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Gansu Lanzhou,Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Gansu Lanzhou,Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Gansu Lanzhou,Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Gansu Lanzhou,Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Gansu Lanzhou |
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Abstract: | |
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Keywords: | Curcumin A549 Network Meta-analysis |
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