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补肾活血方药联合低分子肝素干预早期复发性流产血栓前状态的临床观察
引用本文:李久现,胡小芳,韩永梅,王晶,郭婧. 补肾活血方药联合低分子肝素干预早期复发性流产血栓前状态的临床观察[J]. 上海中医药杂志, 2017, 51(10): 69-71
作者姓名:李久现  胡小芳  韩永梅  王晶  郭婧
作者单位:河南中医药大学第一附属医院生殖医学科,河南郑州,450000,河南中医药大学第一附属医院生殖医学科,河南郑州,450000,河南中医药大学第一附属医院生殖医学科,河南郑州,450000,河南中医药大学第一附属医院生殖医学科,河南郑州,450000,河南中医药大学第一附属医院生殖医学科,河南郑州,450000
摘    要:  目的:观察补肾活血方药联合低分子肝素治疗血栓前状态所致复发性流产的临床疗效。  方法:将90例血栓前状态所致复发性流产的患者随机分为治疗组和对照组,每组45例。在基础黄体支持治疗基础上,治疗组加予补肾活血方药联合低分子肝素治疗,对照组加予低分子肝素治疗。两组疗程均为30日,观察比较孕12周胚胎存活率、凝血相关指标纤维蛋白原(FIB)及D-二聚体(D-Dimer)水平的变化情况。  结果:①治疗组孕12周胚胎存活率为86.67%,对照组为71.11%,组间孕12周胚胎存活率比较,差异有统计学意义,治疗组明显高于对照组(P<0.05)。②治疗前后组内比较,两组FIB、D-Dimer水平差异有统计学意义 (P<0.05);组间治疗后比较,FIB、D-Dimer水平差异有统计学意义,治疗组明显低于对照组(P<0.05)。  结论:补肾活血方药联合低分子肝素治疗早期复发性流产血栓前状态的疗效满意,可显著改善患者的血栓前状态,提高保胎成功率。

关 键 词:复发性流产  早期  血栓前状态  丹参注射液  寿胎丸  肾虚血瘀证  保胎
收稿时间:2017-04-16

Clinical observation of recipes with effects of tonifying kidney and promoting blood circulation combined with low molecular weight heparin on prethrombotic state in early recurrent spontaneous abortion
LI Jiu-xian,HU Xiao-fang,HAN Yong-mei,WANG Jing and GUO Jing. Clinical observation of recipes with effects of tonifying kidney and promoting blood circulation combined with low molecular weight heparin on prethrombotic state in early recurrent spontaneous abortion[J]. Shanghai Journal of Traditional Chinese Medicine, 2017, 51(10): 69-71
Authors:LI Jiu-xian  HU Xiao-fang  HAN Yong-mei  WANG Jing  GUO Jing
Affiliation:Department of Reproductive Medicine,the First Hospital Affiliated to Henan University of Chinese Medicine,Zhengzhou,450000,Department of Reproductive Medicine,the First Hospital Affiliated to Henan University of Chinese Medicine,Zhengzhou,450000,Department of Reproductive Medicine,the First Hospital Affiliated to Henan University of Chinese Medicine,Zhengzhou,450000,Department of Reproductive Medicine,the First Hospital Affiliated to Henan University of Chinese Medicine,Zhengzhou,450000 and Department of Reproductive Medicine,the First Hospital Affiliated to Henan University of Chinese Medicine,Zhengzhou,450000
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