创伤失血性休克液体复苏与控制性升压的临床研究

目的:研究不同液体复苏方法及控制性升压在创伤失血性休克救治中的作用效果。方法:选取159例创伤失血性休克病例,分为限制性液体复苏组85例和正压液体复苏组74例,入院后给与液体复苏,记录复苏液量、时间、复苏后血红蛋白含量及红细胞压积、凝血酶原时间及C-反应蛋白的水平,统计入院2周内本组病例并发症的发生情况及病死率。结果:限制性液体复苏组在入院2周内发生并发症及病死率上低于正压液体复苏组,所需复苏液量小、复苏时间短,凝血酶原时间更短、C-反应蛋白的水平更低,差异均有统计学意义(P<0.05)。结论:限制性液体复苏及控制性升压治疗出血未控制性休克疗效显著。

The clinical research of fluid resuscitation and controlled boost in traumatic hemorrhagic shock

Objective: To explore the effect of limited fluid resuscitation in the treatment of traumatic hemorrhagic shock.Methods: 159 patients with traumatic hemorrhagic shock were randomly divided into control group of 74 cases and observation group of 85 cases.As arrived at hospital,the patients were treated with fluid resuscitation.The infusion fluid volume,recovery time,hemoglobin content,prothrombin time and C-reactive protein were observed in two groups;the occurrence of complications and mortality within two weeks were statisticed.Results: The complications and mortality in two weeks of limited fluid resuscitation group are lower than the positive pressure group,also in the limited fluid resuscitation group the prothrombin time is shorter and C-reactive protein levels are lower,the results are statistically significant(P<0.05).Conclusion: Fluid resuscitation and controlling boost were effective in treating uncontrolled hemorrhagic shock.