| 加味桃红四物汤治疗慢性湿疹临床研究 |
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| 引用本文： | 曹毅,王友力,陶茂灿,罗宏宾,王莉.加味桃红四物汤治疗慢性湿疹临床研究[J].中华中医药杂志,2011(2):253-255. |
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| 作者姓名： | 曹毅 王友力 陶茂灿 罗宏宾 王莉 |
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| 作者单位： | 浙江中医药大学附属第一医院;浙江省诸暨市中医院; |
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| 基金项目： | 浙江省中医药管理局(No.2008CA013)~~ |
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| 摘 要： | 目的:观察加味桃红四物汤治疗慢性湿疹的疗效,以及治疗慢性湿疹的作用机制。方法:严格根据血虚风燥型慢性湿疹的纳入标准选取100例患者,随机分为治疗组和对照组,每组50例,治疗组给予加味桃红四物汤内服,对照组给予西替利嗪口服,4周后分别观察皮损EASI(eczema area and severity index)评分改善情况,以及血清超氧化物歧化酶(superoxide dismutase,SOD)及丙二醛(maleic dialdehyde,MDA)指标的变化情况。结果:加味桃红物汤治疗组总有效率(82.00%)明显高于对照组(52.00%),且血清SOD高于治疗前,MDA低于治疗前(P<0.01)。结论:加味桃红四物汤能有效改善慢性湿疹的临床症状和体征,其机制可能是降低血MDA、升高血清SOD以改善机体氧化状态起到治疗作用。
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| 关 键 词： | 加味桃红四物汤 慢性湿疹 临床研究 |
Clinical study of treatment of chronic eczema by modified Taohong SiwuTang |
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| CAO Yi,WANG You-li,TAO Mao-can,LUO Hong-bin,WANG Li.Clinical study of treatment of chronic eczema by modified Taohong SiwuTang[J].China Journal of Traditional Chinese Medicine and Pharmacy,2011(2):253-255. |
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| Authors: | CAO Yi WANG You-li TAO Mao-can LUO Hong-bin WANG Li |
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| Institution: | CAO Yi1,WANG You-li2,TAO Mao-can1,LUO Hong-bin1,WANG Li1(1The First Affiliated Hoapital of Zhejiang Chinese Medical University,Hangzhou 310006,China,2Zhuji Hospital of Chinese Medicine of Zhejiang Province,Zhuji 311800,China) |
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| Abstract: | Objective: To observe the clinical effect of modified Taohong Siwu Tang and the mechanism in the treatment of chronic eczema.Methods: According to strict inclusion criteria,100 patients with blood deficiency and wind-dryness chronic eczema were randomly divided into treatment group and control group equally.The treatment group took modified Taohong Siwu Tang orally,and the control group took cetirizine orally.The improvement of eczema skin lesions were observed with PASI score before and after four weeks of... |
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| Keywords: | Modified modified Taohong Siwu Tang Chronic eczema Clinical research |
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