| 不同频率电针对实验性肥胖大鼠脂代谢的影响 |
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| 引用本文： | 赵志国,肖红玲,孙立虹,吴中秋,张书义. 不同频率电针对实验性肥胖大鼠脂代谢的影响[J]. 中华中医药杂志, 2011, 0(1): 183-186 |
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| 作者姓名： | 赵志国 肖红玲 孙立虹 吴中秋 张书义 |
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| 作者单位： | 河北医科大学中医学院; |
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| 基金项目： | 河北省科技攻关计划项目(No.062761376); 河北省中医药管理局科学研究计划项目(No.2009006)~~ |
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| 摘 要： | 目的:通过观察不同频率的电针对实验性肥胖大鼠脂代谢的影响,探讨频率调节脂代谢异常的作用机制。方法:采用谷氨酸钠和高脂饮食诱导的下丘脑性肥胖大鼠模型,选取大鼠曲池、丰隆、三阴交、后三里、中脘和关元穴,采用2Hz、50Hz、100Hz频率针刺。测定大鼠体质量指数(Lee,s指数)、左肾周脂肪和大网膜脂肪湿重;用酶学终点法测血清三酰甘油(TG)、胆固醇(TC)的含量;用磷钨酸-镁沉淀法测血清高密度脂蛋白胆固醇(HDL-C)含量;用聚乙烯硫酸沉淀法测血清低密度脂蛋白胆固醇(LDL-C)含量。结果:与模型组比较,电针3组大鼠Lee,s指数、左肾周脂肪和大网膜脂肪湿重、血清TG、TC和LDL-C含量均显著降低(P<0.05或P<0.01),血清HDL-C含量显著升高(P<0.05)。结论:2Hz、50Hz、100Hz电针频率降低大鼠Lee,s指数、调整脂代谢的作用有依次递减的趋势,50Hz电针频率似在降低脂肪重量上较2Hz和100Hz有优势。
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| 关 键 词： | 电针 频率 肥胖 Lee,s指数 脂代谢 大鼠 实验研究 |
Effect of different-frequency electroacupuncture on lipid metabolism in obesity rats |
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| ZHAO Zhi-guo,XIAO Hong-ling,SUN Li-hong,WU Zhong-qiu,ZHANG Shu-yi. Effect of different-frequency electroacupuncture on lipid metabolism in obesity rats[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2011, 0(1): 183-186 |
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| Authors: | ZHAO Zhi-guo XIAO Hong-ling SUN Li-hong WU Zhong-qiu ZHANG Shu-yi |
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| Affiliation: | ZHAO Zhi-guo,XIAO Hong-ling,SUN Li-hong,WU Zhong-qiu,ZHANG Shu-yi (The TCM College,Hebei Medical University,Shijiazhuang 050091,China) |
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| Abstract: | Objective: To observe the effect of different-frequency electroacupuncture on lipid metabolism in obesity rats,and to analyze the regulation mechanism of frequency to the disorder of Lipid Metabolism.Methods: The hypothalamus obesity rat model was induced by sodium glutaminic acid and high lipoprotein diet,adopt 2Hz,50Hz and 100Hz frequency to acupuncture quchi,fenglong,sanyingjiao,housanli,zhongwan and guanyuan.To determine the rat's weight index(Lee's index),the wet weight of left kidney cycle and big ome... |
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| Keywords: | Electric needle Frequency Obesity Lee's index Lipid metabolism Rats Experiment study |
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