|
|||||
|
|
| 改变食物硬度对大鼠生长早期髁突软骨中VEGF、aggrecanase-1和TIMP-3mRNA表达的影响 | |
| 引用本文： | 李煜,黄慧萍,于大海,李晶. 改变食物硬度对大鼠生长早期髁突软骨中VEGF、aggrecanase-1和TIMP-3mRNA表达的影响[J]. 实用口腔医学杂志, 2011, 27(6): 752-756. DOI: 10.3969/j.issn.1001-3733.2011.06.04 |
| 作者姓名： | 李煜 黄慧萍 于大海 李晶 |
| 作者单位： | 广西医科大学附属口腔医院口腔颌面外科,南宁,530021 |
| 基金项目： | 广西自然科学基金资助项目(编号:桂科回0731017) |
| 摘 要： | 目的:通过改变食物硬度造成大鼠生长早期颞下颌关节软骨的负荷改变,检测髁突软骨中血管内皮生长因子(vascular endothelial growth factor,VEGF)、聚集蛋白聚糖酶-1(aggrecanase-1)和金属蛋白酶抑制剂因子-3(tissue inhibitor of metalloprotei... |
| 关 键 词： | 血管内皮生长因子 聚集蛋白聚糖酶-1 金属蛋白酶抑制因子-3 髁突软骨 食物负荷 |
The effects of dietary loading on VEGF,aggrecanase-1 and TIMP-3 mRNA expressions in rat mandibular condylar cartilage in early growth stage |
|
| LI Yu,HUANG Huiping,YU Dahai,LI Jing. The effects of dietary loading on VEGF,aggrecanase-1 and TIMP-3 mRNA expressions in rat mandibular condylar cartilage in early growth stage[J]. Journal of Practical Stomatology, 2011, 27(6): 752-756. DOI: 10.3969/j.issn.1001-3733.2011.06.04 | |
| Authors: | LI Yu HUANG Huiping YU Dahai LI Jing |
| Affiliation: | LI Yu,HUANG Huiping,YU Dahai,LI Jing.530021 Nanning,Department of Oral and Maxillofacial Surgery,College of Stomatology,Guangxi Medical University,China |
| Abstract: | Objective: To investigate the effects of dietary loading on VFGF,aggrecanase-1 and TIMP-3 expression in mandibular condylar cartilage of rats in early growth stage.Methods: 40 SD rats aged 28 d were randomly assigned into two groups: soft-diet group(n=20) and hard-diet group(n=20).5 rats in each group were killed at 24 h,48 h,7 and 14 days respectively after initiation of diet change.VEGF,aggrecanase-1 and TIMP-3 mRNA expressions in whole condyle cartilage were detected by semi-quantitative RT-PCR.Results: ... |
| Keywords: | Vascular endothelial growth factor(VEGF) Aggrecanase-1 Tissue inhibitor of metalloproteinase-3(TIMP-3) Mandibular condylar cartilage Dietary loading |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |