| 耐药结核病的分子生物学研究进展 |
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| 引用本文： | 吴长东,袁俐.耐药结核病的分子生物学研究进展[J].中国寄生虫病防治杂志,2009(12):943-945. |
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| 作者姓名： | 吴长东 袁俐 |
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| 作者单位： | 新疆石河子大学医学院病原微生物与免疫学教研室,新疆石河子832002 |
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| 摘 要： | 结核病是一个严重的全球公共卫生问题,每年有超过40万耐多药结核病新病例的发生。利用分子生物学方法,从基因水平阐明结核分枝杆菌耐药性的机理,并在此基础上建立敏感、快速和特异的检测方法成为耐药结核病研究的重点。本文就耐药结核病的分子生物学研究现状进行概述。
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| 关 键 词： | 结核分枝杆菌 耐药结核病 耐多药结核病 泛耐药结核病 分子生物学 |
Advances in research on the molecular biology of drug-resistant tuberculosis |
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| WU Chang-dong,YUAN Li.Advances in research on the molecular biology of drug-resistant tuberculosis[J].Chinese Journal of Parasitic Disease Control,2009(12):943-945. |
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| Authors: | WU Chang-dong YUAN Li |
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| Institution: | (College of Medicine, Shihezi University, Shihezi 832002, Xinjiang, China) |
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| Abstract: | Tuberculosis（TB）is a serious public health problem worldwide,with over 400 000 new cases of multidrug-resistant tuberculosis（MDR-TB） occuring every year.The study of drug-resistant tuberculosis uses methods of molecular biology to clarify the mechanisms of drug-resistance of Mycobacterium tuberculosis on the genetic level,and the field focuses on establishing sensitive,rapid,and specific methods of detecting MDR-TB.This article reviews recent studies on the molecular biology of drug-resistant tuberculosis. |
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| Keywords: | Mycobacterium tuberculosis drug-resistant tuberculosis multidrug-resistant tuberculosis extensively drug-resistant tuberculosis molecular biology |
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