Immunoregulatory subpopulations of T-lymphocytes and their distribution in the peripheral blood, lymph nodes and spleen of patients with lymphogranulomatosis

Monoclonal antibodies OKT 3, OKT 4 and OKT 8 were used in 20 patients with Hodgkin's disease in order to characterize lymphocyte subpopulations in the peripheral blood, lymph nodes and spleen. As compared to the normal donors' peripheral blood and other parameters, the content of the OKT 3+, OKT 4+ cells in the involved lymph nodes and in the splenocyte suspension turned out to be high.