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胆道闭锁15例
引用本文:胡婷嫣,赵夷,张志波,王练英,黄英. 胆道闭锁15例[J]. 实用儿科临床杂志, 2010, 0(3)
作者姓名:胡婷嫣  赵夷  张志波  王练英  黄英
作者单位:中国医科大学附属盛京医院小儿外科;中国医科大学附属盛京医院第一微创胆道外科;
摘    要:
目的探讨胆道闭锁(BA)的临床特点、治疗与预后的关系。方法回顾性分析经中国医科大学附属盛京医院小儿外科近2 a来诊治的15例BA患儿的临床症状、体征、实验室检查结果,诊断、治疗经过及预后,并结合文献报道,对其发病原因、治疗经验、疾病转归及预后进行综合分析。结果男9例,女6例;年龄28~90 d。胆总管闭锁型(Ⅰ型)、肝管闭锁型(Ⅱ型)各3例,肝门区胆管闭锁型(Ⅲ型)8例,胆总管闭锁并先天性肠旋转不良1例。11例生后即出现黄疸,4例出生1周内逐渐发生黄疸。大便进行性变浅或表现为陶土样便13例,2例生后2 d即排陶土样便。15例胆红素水平均有升高,且排泄性肝胆超声均表现为胆囊收缩不良。并巨细胞病毒感染14例,感染率为93%。患儿均行手术治疗,术后病理结果均表现为胆汁淤积性肝硬化。10例患儿术后6~28 d出院,5例患儿术后2 d家属放弃治疗出院。目前随访患儿共12例,随访时间1个月~1.5 a,生长发育均良好,9例有黄疸,10例有黄绿色便排出,2例排陶土样便,4例Ⅰ型和3例Ⅱ型的BA患儿胆红素水平术后可降至正常水平,2例Ⅲ型BA患儿胆红素在术后1个月左右降至正常水平,但反复发生毛细胆管炎。结论BA的病因与病毒感染...

关 键 词:胆道闭锁  病因  诊断  治疗  预后  

Fifteen Cases of Biliary Atresia
HU Ting-yan,ZHAO Yi,ZHANG Zhi-bo,WANG Lian-ying,HUANG Ying. Fifteen Cases of Biliary Atresia[J]. Journal of Applied Clinical Pediatrics, 2010, 0(3)
Authors:HU Ting-yan  ZHAO Yi  ZHANG Zhi-bo  WANG Lian-ying  HUANG Ying
Affiliation:HU Ting-yan1,ZHAO Yi2,ZHANG Zhi-bo1,WANG Lian-ying1,HUANG Ying1(1.Department of Pediatric Surgery,Shengjing Hospital of China Medical University,Shenyang 110004,Liaoning Province,China,2.Department of General Surgery Ward of the First Minimal-Invasive , Biliary Tract Disease,Shenyang,China)
Abstract:
Objective To discuss the relationship between clinical features,treatment and prognosis of biliary atresia(BA).Methods Clinical symptoms,physical signs,chemical examinations,diagnosis,treatment and prognosis of 15 cases of BA,who were cured by Shengjing Hospital of China Medical University in the past 2 years,were retrospectively analyzed,and related papers were also reviewed in pathogenesis,treatment and prognosis.Results Nine cases of male,6 cases of female,aged between 28 days and 90 days.Bile common duc...
Keywords:biliary atresia  etiology  diagnosis  treatment  prognosis  
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