腹腔镜胃十二指肠溃疡穿孔修补术的临床研究

目的探讨腹腔镜胃十二指肠溃疡穿孔修补术的临床疗效。方法选取2010年6月至2011年6月收治的胃十二指肠溃疡穿孔患者90例,将其随机分为观察组和对照组各45例,观察组采用腹腔镜胃十二指肠溃疡穿孔修补术进行治疗,对照组采用传统开腹手术进行治疗。记录两组的手术时间、术中出血量、术后下床活动时间及住院时间,观察比较溃疡愈合率、远期并发症发生率及随访1年的溃疡复发率。结果观察组患者手术时间、术后下床活动时间及住院时间均短于对照组,术中出血量亦较对照组少,两组各指标比较,差异有统计学意义(P<0.05)。观察组溃疡愈合率为96%,高于对照组的91%,但两组差异无统计学意义(P>0.05);观察组远期并发症发生率为7%,显著低于对照组的27%,两组差异有统计学意义(P<0.05);两组患者均随访1年,观察组溃疡复发率为2%,低于对照组的11%,两组差异有统计学意义(P<0.05)。结论腹腔镜胃十二指肠溃疡穿孔修补术具有较好的临床疗效,手术创伤小、时间短,术中出血量少,患者恢复快、住院时间短,术后并发症发生率低,且随访复发率低,值得临床推广应用。

Clinical study of laparoscopic gastric ulcer perforation repair

Objective To evaluate the clinical efficacy of laparoscopic gastric ulcer perforation repair. Methods Ninety cases of gastric ulcer perforation treated in our hospital from June 2010 to June 2011 were selected and randomly divided into observation group and control group, with 45 patients in each group. The observation group was given laparoscopic gastric duodenal ulcer perforation repair and control group was given traditional open surgery. The operative time, blood loss, postoperative ambulation time and hospital stay were recorded, ulcer healing rates, the in- cidence of long - term complications and 1 - year ulcer recurrence rate were observed between two groups. Results The mean operative time, postoperative ambulation time and hospital stay of the observation group were shorter than those of the control group, blood loss was less than that of the control group, the differences were statistically significant （ all P 〈 0.05 ）. The ulcer healing rate of observation group was 96% , which was higher than 91% of control group, but the difference was not statistically significant （ P 〉 0.05 ）. The long - term complication rate of observation group was 7%, which was significantly lower than 27% of the control group （ P 〈0.05）. All patients were followed up for 1 year, the ulcer re- currence rate of observation group was 2%, which was less than 11% of the control group （ P 〈 O. 05 ）. Conclusion Laparoscopie gastric ulcer perforation repair has better clinical efficacy, less blood loss and surgical trauma, short operative time and hospital stay, fast recovery, and low postoperative complication rate and recurrence rate. It is worthy of clinical application.