静滴高渗脱水剂引起的眶压和眼球突出度变化

目的了解静滴高渗脱水剂后对眼球突出度和眶压的影响，确定眶压及眼球突出度测量在诊断治疗脱水时的价值。方法对86例单眼白内障需手术者，在静滴200g·L(-1)甘露醇前后进行非手术眼的眶压和眼球突出度测量。结果用药后0．5、2、3h眶压和眼球突出度均显著低于用药前。以用药后2h眶压和眼球突出度最低，与用药前比较，眶压下降0．67kPa（P＜0．01）。眼球突出度下降2．1mm（P＜0．01）。结论用高渗脱水剂可使眶内组织脱水，使眶压和眼球突出度降低，用直接接触式眶压计可同时检测出这种脱水引起的眶压和眼球突出度变化，为诊断治疗脱水提供依据。

Changes of amounts of intraorbital pressure and exophthalmos caused by intravenous infusion of mannitolum

Objectives To evaluate the effects of intravenous in fusion of mannitolum on the degree of intraorbital pressure and exophthalmos and investigate the clinical value of measurement of intraorbital pressure and exophthalmos in the diagnosis and treatment of dehydration.Methods The intraorbital pressure and exophthalmos of the normal eyes of 86 patients whose one eye had cataract and needed surgical treatment were measured before and after intravenous infusion of mannitolum.Results The degree of intraorbital pressure and exophthalmos after infusion of mannitolum was remarkably lower than that before infusion. It reached the lowest in two hours. The intraorbital pressure was decreased by 0. 67 kPa (P<0.01) and the exophthalmos was decreased by 2.1mm (P<0. 01 ).Conclusion Hyperosmotic agents may cause the water loss of the orbital tissue and decrease the intraorbital pressure and exophthalmos. These changes of intraorbital pressure and exophthalmos may be measured by the immediate contact orbitonometer. The measurement of intraorbital pressure and exophthalmos may provide evidence to the diagnosis and treatment of dehydration.