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Monochorionic twin fetus with VACTERL association after intracytoplasmic sperm injection
Authors:Tomonobu Kanasugi  Akihiko Kikuchi  Atsushi Matsumoto  Miyuki Terata  Chizuko Isurugi  Rie Oyama  Akimune Fukushima  Toru Sugiyama
Affiliation:1. Departments of Obstetrics and Gynecology;2. Neonatology, Iwate Medical University School of Medicine, Morioka, Japan
Abstract:
We report a rare case of a monochorionic twin gestation after intracytoplasmic sperm injection (ICSI) in which one of the fetuses had VACTERL association. A 27‐year‐old woman became pregnant by ICSI and was found to have monochorionic twin fetuses. One fetus was noted to have the following anomalies: a multicystic, dysplastic left kidney with a hydroureter, and a dilated colon. A normal‐sized stomach and normal amount of amniotic fluid were observed during the prenatal period with no other anomalies. The postnatal examination revealed hypospadias, and anal, esophageal, and duodenal atresia; thus, a diagnosis of VACTERL association was established. Although the prenatal diagnosis of this disorder is a challenge, even in a singleton, some of the characteristic features observed during antepartum ultrasonography may be a clue to the diagnosis, especially in a twin pregnancy after ICSI.
Keywords:fetal ultrasound  intracytoplasmic sperm injection  monochorionic twin  prenatal diagnosis  VACTERL association
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