特异性免疫治疗对过敏性鼻炎和哮喘的同步控制和远期疗效

近年来,过敏性鼻炎(AR)和哮喘的患病率呈明显增加的趋势。随着对特异性免疫治疗(SIT)的不断了解与深入,目前认为该方法可能是惟一通过调节免疫机制从而改变变应性疾病的自然进程,并且可以在治疗停止之后获得长期疗效。综述了SIT对AR和哮喘的同步控制和远期疗效,通过国内外文献回顾及分析对比,认为SIT在治疗AR和哮喘的过程中起着十分重要且积极的作用,并且能够预防AR向哮喘进展。但是,SIT也存在一些问题,值得进一步研究及探讨。

Synchronous control and long-term efficacy of specific immunotherapy for allergic rhinitis and asthma

In recent years, the prevalence of allergic rhinitis(AR)and allergic asthma has increased significantly. Because of a deeper understanding of specific immunotherapy(SIT), it is currently believed that SIT may be the only treatment that changes the natural course of allergic diseases by regulating the immune mechanisms and can maintain long-term effects after treatment has been discontinued. This article reviews the simultaneous control and long-term efficacy of SIT for AR and asthma. A literature review and analysis of domestic and international studies indicates that SIT plays an important and positive role in the treatment of AR and asthma and can prevent AR from progressing to asthma. However, SIT is also associated with some problems that merit further discussion.