| 液相色谱-串联质谱在全谱氨基酸检测中的应用 |
| |
| 引用本文： | 陶蓓蓓,李鹏飞,张绪得,安卓玲,王燕 刘丽宏. 液相色谱-串联质谱在全谱氨基酸检测中的应用[J]. 分子诊断与治疗杂志, 2012, 4(1): 59-61 |
| |
| 作者姓名： | 陶蓓蓓 李鹏飞 张绪得 安卓玲 王燕 刘丽宏 |
| |
| 作者单位： | 陶蓓蓓 (艾米诺医学研究有限公司,北京,100088) ； 李鹏飞 (第二炮兵总医院药学部,北京,100088) ； 张绪得 (艾米诺医学研究有限公司,北京,100088) ； 安卓玲 (第二炮兵总医院药学部,北京,100088) ； 王燕 (第二炮兵总医院药学部,北京,100088) 刘丽宏 (第二炮兵总医院药学部,北京,100088) |
| |
| 摘 要： | 全谱氨基酸检测是指利用液相色谱串联质谱技术、采用同位素内标的方法,精确测定人体内42种氨基酸含量。全谱氨基酸失衡是众多疾病的诱因或表现形式,涉及代谢、肿瘤、免疫、病毒、心脑血管、神经系统、肾病、糖尿病、亚健康、老年病等各类疾病和儿童生长发育、营养健康、肌肉骨骼生长、激素分泌、解毒功能等人体各种健康环节。
|
| 关 键 词： | 全谱氨基酸 液相色谱 串联质谱 |
Liquid chromatography-tandem mass spectrometry in the full spectrum of amino acid detection |
| |
| TAO Beibei,LI Pengfei,ZHANG Xude,AN Zhuoling,WANG Yan,LIU Lihong. Liquid chromatography-tandem mass spectrometry in the full spectrum of amino acid detection[J]. Journal of Molecular Diagnosis and Therapy, 2012, 4(1): 59-61 |
| |
| Authors: | TAO Beibei LI Pengfei ZHANG Xude AN Zhuoling WANG Yan LIU Lihong |
| |
| Affiliation: | 1. Beijing Amino Medical Research CO., LTD, Beijing 100088, China; 2. Pharmacy Department of the Second Artillery General Hospital, Beijing 100088, China) |
| |
| Abstract: | Liquid chromatography combined with tandem mass spectrometry and isotope internal standard method can be used for accurate determination of 42 kinds of amino acids in human body. The imbalance of the full spectrum of amino acids is one of incentives or manifestations of many diseases involved in metabolism, cancer, immune, viral, cardiovascular, nervous system, kidney disease, diabetes, sub-health, old age diseases and other diseases, and child growth and development, nutrition and health, musculoskeletal growth, hormone secretion, and detoxification functions. |
| |
| Keywords: | The full spectrum of amino acids Liquid chromatography Tandem mass spectrometry |
| 本文献已被 维普 等数据库收录！ |
|
