输卵管性不孕的高危因素分析

目的:探讨输卵管性不孕(TFI)的病因,并为其预防和临床治疗提供参考依据。方法:采用病例-对照研究方法,病例组为在弋矶山医院确诊为输卵管性不孕妇女,对照组为在妇产科人流妇女。两者均填写统一调查表,并检测衣原体(CT)、支原体(UU)。资料采用非条件Logistic回归分析。结果;病例组衣原体、支原体感染(25.7%、18.8%)明显高于对照组(6.7%、2.5%)。危险因素为:初次性生活年龄20岁(OR:3.373)、性伴侣数1人(OR:3.056)、人流史(OR:1.057)、输卵管妊娠史(OR:6.579)、宫颈炎(OR:2.890)、盆腔炎史(OR:6.488)、结核史(OR:4.986)、阑尾炎史(OR:4.915)。结论:UU、CT感染,初次性生活年龄过小、性伴侣多、输卵管妊娠史、宫颈炎、盆腔炎史、结核史、阑尾炎史是输卵管性不孕的危险因素。人流史与TFI无显著相关。

Analysis on high risk factors of tubal infertility

Objective:To explore the causes of tubal infertility,and provide a basis for prevention and clinical treatment.Methods:A case-control study was used;the women diagnosed as tubal infertility in the hospital were selected as case group,the women undergoing artificial abortion in department of gynecology and obstetrics were selected as control group;all the cases were asked to finish a uniform questionnaire,the infection rates of chlamydia and mycoplasma were detected;the data were analyzed with non-conditional logistic regression analysis.Results:The infection rates of chlamydia and mycoplasma in case group(25.7% and 18.8%,respectively) were significantly higher than those in control group(6.7% and 2.5%,respectively).The risk factors of tubal infertility included the age of first sex life<20(OR:3.373),the number of sexual partners>1(OR:3.056),the history of induced abortion(OR:1.057),the history of salpingocyesis(OR:6.579),cervicitis(OR:2.890),the history of pelvic inflammation(OR:6.488),the history of tuberculosis(OR:4.986) and the history of appendicitis(OR:4.915).Conclusion:The risk factors of tubal infertility include:chlamydia and mycoplasma infection,first sex life at early age,more than one sexual partner,and the histories of salpingocyesis,cervicitis,pelvic inflammation,tuberculosis and appendicitis,while there is no significant correlation between the history of induced abortion and tubal infertility.