郑州市正常新生儿脑组织氧饱和度正常参考值范围的研究

目的:探讨近红外光谱测定技术(near-infrared spectroscopy,NIRS)检测正常新生儿局部脑组织氧饱和度(regional oxygen saturation,rSO2),建立新生儿脑rSO2的正常值参考值范围。方法:应用TSAH-100型近红外组织血氧参数无损监测仪,测定我院正常新生儿出生后1、2、3、10~15天时的脑组织氧饱和度变化,并进行比较。结果:正常新生儿脑rSO2在出生后第1天为(62.02±2.86)%、第2天为(62.06±2.40)%、第3天为(61.91±2.29)%、第10天后为(61.96±2.40)%,比较差异无统计学意义(P>0.05);不同性别正常新生儿的rSO2在出生后第2、3、10天比较差异有统计学意义(P<0.05);rSO2与SPO2总体呈正相关。结论:郑州市正常足月新生儿脑rSO2测定值参考范围为(62.03±2.51)%,如果低于57.9%则提示有脑组织缺氧。

Study on range of normal reference value of cerebral oxygen saturation in healthy neonates in Zhengzhou city

Objective:To establish range of normal reference value of cerebral oxygen saturation in healthy neonates by detecting regional cerebral oxygen saturation(rSO2)using near-infrared spectroscopy.Methods:The changes of rSO2 of healthy neonates were detected by TSH-100 near infrared speetrophotometry human tissue oximeter at the l,2,3,10~15 days after birth,then the results were compared.Results:The rSO2 values at the l,2,3,10~15 days after birth were(62.02±2.86)%,(62.06±2.40)%,(61.91±2.29)% and(61.96±2.40)%,respectively,there was no significant difference;there was significant difference in rSO2 values at the 2,3,10 days between boys and girls(P<0.05);there was positive correlation between rSO2 and SpO2.Conclusion:The range of normal reference value of rSO2 in healthy neonates in Zhengzhou city is(62.03±2.51)%,normal reference value<57.9% indicates hypoxia of brain tissue.