| Cloning and analysis of the envelope protein clone of HIV-1, CHNHLJ03009c34 from an infected individual in Heilongjiang province |
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| 引用本文： | TOSHIO HATTORI. Cloning and analysis of the envelope protein clone of HIV-1, CHNHLJ03009c34 from an infected individual in Heilongjiang province[J]. 中华微生物学和免疫学杂志(英文版), 2005, 3(4): 254-259 |
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| 作者姓名： | TOSHIO HATTORI |
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| 作者单位： | Division of |
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| 摘 要： | ![]()
Envelopeglycoprotein(Env)ofHIV1isacom plexoftwononcovalentlyassociatedsubunits,Gp120andGp41.Gp120isanexternalsubunit thatbindsthecellularreceptorCD4andachemo kinereceptor,suchasCXCR4orCCR5.Gp41isatransmembranesubunit,responsibleforthere ceptor mediatedmembranefusion[1,2].Because ofthehighvariabilityofHIV1,theaminoacid sequenceaswellasthestructureofviralenvelope canvaryandresultinthechangeofviraltropism withtimeextensionanddiseaseprogressionafter infection.DuringtheearlyphaseofHIVinfec…
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| 关 键 词： | 蛋白质 克隆技术 HIV 爱滋病病毒 CHNHLJ03009c34 黑龙江 |
Cloning and analysis of the envelope protein clone of HIV-1, CHNHLJ03009c34 from an infected individual in Heilongjiang province |
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| HAI ZHOU ZHOU YAN LI HONG LING YAN CHENG LIU BING CHENG HUANG TOSHIO HAITORI. Cloning and analysis of the envelope protein clone of HIV-1, CHNHLJ03009c34 from an infected individual in Heilongjiang province[J]. Chinese Journal of Microbiology and Immunology, 2005, 3(4): 254-259 |
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| Authors: | HAI ZHOU ZHOU YAN LI HONG LING YAN CHENG LIU BING CHENG HUANG TOSHIO HAITORI |
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| Affiliation: | [1]Department of Microbiology [2]Department of Parasitology, Harbin Medical University, Harbin, P. R.China [3]Heilongjiang Center for Disease Control and Prevention, Harbin, P. R. China [4]Division of Infectious and Respiratory Diseases, Department of Internal Medicine, Graduate School ofMedicine, Tohoku University, Japan |
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| Abstract: | ![]()
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| Keywords: | Human immunodeficiency virus type 1 (HIV-1) Envelope Variability Subtype Infection |
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