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The Rotterdam Study: objectives and design update |
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| Authors: | Albert Hofman Monique M. B. Breteler Cornelia M. van Duijn Gabriel P. Krestin Huibert A. Pols Bruno H. Ch. Stricker Henning Tiemeier André G. Uitterlinden Johannes R. Vingerling Jacqueline C. M. Witteman |
| Affiliation: | (1) Department of Epidemiology & Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands;(2) Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands;(3) Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands;(4) Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands |
| Abstract: | The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in the Netherlands. The study targets cardiovascular, neurological, ophthalmological and endocrine diseases. As of 2008 about 15,000 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in some 600 research articles and reports (see ). This article gives the reasons for the study and its design. It also presents a summary of the major findings and an update of the objectives and methods. |
| Keywords: | Alzheimer disease Cohort study Dementia Diabetes Genome wide analysis Glaucoma Heart failure Macular degeneration Myocardial infarction Osteoporosis Parkinson disease Pharmaco-epidemiology Stroke |
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