应用单纯自固化磷酸钙人工骨修复小儿良性骨肿瘤术后骨缺损

目的　探讨应用单纯自固化磷酸钙人工骨 (CPC)修复小儿良性骨囊肿术后骨缺损的临床效果。　方法　 1998年 12月～ 2 0 0 2年 5月随机选取 2 2例良性骨肿瘤患儿 ,男 18例 ,女 4例 ,年龄 4～ 10岁 ,平均 8.3岁。其中非骨化性纤维瘤 11例 ,骨样骨瘤 7例 ,骨囊肿 2例 ,纤维异样增殖症 2例。骨缺损部位 :股骨 14例 ,胫骨 6例 ,肱骨 2例。骨缺损范围 :2 cm× 2 cm× 3cm～ 3cm× 3cm× 6 cm。其中 2 0例采用病灶清除后 CPC松质骨粒填充 ,2例骨囊肿采用穿刺抽液后注射可注射型 CPC。随访时间 :5～ 4 8个月 ,平均 2 3.5个月。　结果　 2 2例均获随访 ,术后均无过敏及毒性反应 ,切口局部无异常 ,骨质生长良好 ,无 1例复发 ,患儿肢体活动正常。　结论　应用单纯 CPC修复小儿良性骨肿瘤术后骨缺损是一种安全、经济、无损伤和简便的方法。

REPAIR OF BONE DEFECT DUE TO TUMOUR RESECTION WITH SELF-SETTING CALCIUM PHOSPHATE CEMENT IN CHILDREN

Objective To study the effect of self-setting calcium phosphate cement (CPC) on the repair of local bone defects after resection of cyst in children. Methods From December 1998 to May 2002, 22 patients with bone defects were repaired with CPC. Their ages ranged from 4 to 10 years with an average of 8.3 years. There were 11 cases of non-ossifying fibroma, 7 cases of osteoid osteoma, 2 cases of bone cyst and 2 cases of fibrous dysplasia. The bone defects are located as the following: femur in 14 cases, tibia in 6 cases and humerus in 2 cases. CPC spongiosa granules were filled in 11 cases, injectable CPC were filled in 2 bone cyst cases. The patients were followed up for 5-48 months, averaged 23.5 months. Results Bone matrix grew well and no recurrence was found. Conclusion The method with simple CPC in repairing bone defects is safe, non-toxic, economic and convenient in children.