孤立性纤维性肿瘤临床病理分析

目的探讨孤立性纤维性肿瘤的临床病理特点，提高对该病的认识。方法对13例孤立性纤维性肿瘤进行病理形态学观察、免疫组织化学检测，并结合临床进行分析。结果本组发病年龄16～68岁，平均45岁；8例为男性，5例为女性。发生部位包括软组织、腹腔、纵隔、胸膜、肺部等。临床表现主要为局部肿块及其压迫症状。肿瘤直径1．5．20cm，多数边界较清；显微镜下瘤细胞以梭形细胞为主，具有细胞致密区与稀疏区，间质可见瘢痕样胶原及分支状的血管外皮瘤样结构，瘤细胞排列方式多样；免疫组化结果：Vimentin，Bcl-2阳性均为13例、CD34阳性11例、CD99阳性10例。结论孤立性纤维性肿瘤是一种少见肿瘤，可发生在全身各部位，多为良性，极少部分为恶性，组织学构象并不能完全预测其生物学行为，其预后还取决于肿瘤的大小和生长方式，完全切除肿瘤者预后一般较好，定期随访是必要的。

Clinicopathologic Analysis of Solitary Fibrous Tumor

Objective To study the clinical and pathological features of solitary fibrous tumor(SFT) and improve the diagnosis of the SFT.Methods The clinical and pathological characteristics were studied by hematoxylin and eosin staining and immunohistochemical staining(Envision method) in 13 cases of SFT.Results The 8 male and 5 female patients were between 16 and 68 years of age(mean45).Their SFT were located in soft tissue,abdominal cavity,mediastinum,pleura,and lung.The main clinical manifestations were local mass...