老年性血管性痴呆与脑白质疏松的相关研究

目的　探讨老年性血管性痴呆 (VD)与脑白质疏松症 (LA)的相关性。方法　对 5 4例 6 0岁以上LA患者的临床及CT和 /或MRI进行 3年跟踪观察 ,应用分级法观察LA的损伤程度 ;应用MMSE和Hachinski量表诊断VD。结果　 5 4例LA患者损伤程度Ⅰ～Ⅲ级变化分别为第 1年 34、14、6例 ,第 2年 17、19、18例 ,第 3年 8、17、2 9例。患老年性VD者第 1年 6例 ,第 2年 13例 ,第 3年 33例 ,平均年增长率为 32 %。结论　LA是老年性VD发生的早期危险信号 ,LA的损伤程度与老年性VD的发生呈正相关 (r=0 .82 ,P <0 .0 5 ) ,应当积极预防和治疗。

Study on the relationship between vascular dementia in senitity and diffuse white matter lucencice

Objective To analyse the relationship between vascular dementia in senitity and diffuse white matter lucencice.Methods Observing 54 patients older than 60 of diffuse white matter lucencice for three years with clinical methods CT and/or MRI.Diagnosing vascular dementia by MMSE and Hachinski.Results The degree of diffuse white matter lucencice within the 54 patients were 34 cases as first degree,14 cases as second degree, 6 cases as third degree in the first year, 17 cases, 19 cases and 18 cases in the second year restectively, 8 cases, 17 cases and 29 cases in the third year.The 6 cases of group suffer from the vascular dementia in senitity in the first year,13 cases in the second year,33 cases in the third year.The average annual growth was 32%.Conclusion Diffuse white matter lucencice is a critical factor of vascular dementia in senitity. The positive correlation between the degree of diffuse white matter lucencice and the occurrence of vascular dementia in senitity has been shown( r =0.82, P <0.05), the active prevention and early treatment for diffuse whitematter lucencice should be recommended.