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胃肠道间质瘤的分子生物学研究
引用本文:侯英勇,朱雄增. 胃肠道间质瘤的分子生物学研究[J]. 肿瘤研究与临床, 2006, 18(8): 507-512
作者姓名:侯英勇  朱雄增
作者单位:1. 200032,上海,复旦大学附属中山医院病理科
2. 复旦大学附属肿瘤医院病理科
基金项目:国家自然科学基金青年科学基金资助项目(30300152)
摘    要:
 胃肠道间质瘤(GIST)是新近得以深入认识的肿瘤,尤其在GIST分子生物学研究领域获得的重要进展被迅速运用到临床诊断及治疗中,使基础研究与临床应用紧密结合。GIST的分子遗传学机制也是新型分子靶向治疗的研究和应用获得成功的又一典范,因此,GIST日益受到学者们的广泛关注,文章主要对GIST的分子生物学研究进展作一介绍。

关 键 词:胃肠道间质瘤  分子生物学
文章编号:1006-9801(2006)08-0507-06
收稿时间:2006-04-15
修稿时间:2006-04-15

Molecular and biologic study of gastrointestinal stromal tumors
HOU Ying-yong,ZHU Xiong-zeng. Molecular and biologic study of gastrointestinal stromal tumors[J]. Cancer Research and Clinic, 2006, 18(8): 507-512
Authors:HOU Ying-yong  ZHU Xiong-zeng
Affiliation:Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Abstract:
Gastrointestinal stromal tumors is a new kind of tumor known recently, especially the important progress in the molecular and biologic study of GIST were used quickly in the clinical diagnosis and treatment, and made a close combination of basic research and clinical applications. The study and application of target therapy of new molecules on the mechanism of molecular genetics of GIST was another successful example. Therefore, GIST was paid extensive attention by the scholars. The progress on the molecular and biological study was summarized.
Keywords:Molecular and biologic study   Gastrointestinal stromal tumors
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