Quisi与睡眠脑电图检测抑郁症的比较研究

目的评价Quisi检测抑郁症的作用和适应证。方法对19例抑郁症患者和21名正常受试者分别作Quisi和睡眠脑电图检测。并以日本SEEG-1500型睡眠脑电图为检测标准,与德国Quisi进行比较研究。结果在正常对照组中,除睡眠第二阶段百分比,Quisi少于多导睡眠图(Polysomnography,PS)外(Quisi为48±8,正常人PSG56±9,t=2.48,P<0.05),其余12项指标差异均无显著性。抑郁症组中睡眠第一阶段百分比,Quisi也少于PSG(Quisi为11±4,PSG为13±3,t=2.0,P<0.05),其余12项指标差异也无显著性。结论Quisi检测抑郁症作用与PSG相似,在心理咨询、外出巡诊和家庭病床上有应用前途,但不适用于发作性疾病的评估。

Quisi method and sleep electroencephalogram in evaluation of depression

Aim To assess the efficacy of Quisi in evaluating depression and its application.Methods Sleep electroencephalograms(EEG) were obtained from 19 patients,10 males and 9 females with an average age of(31± 7) years,and 21 controls,11 males and 10 females with an average age of (38± 8) years,using German Quisi and Japanese PSG.Based on the Japanese-SEEG-1500-type sleep EEG,sleep EEGs recorded from Quisi was analyzed.Results In the control group,S2 percentage from Quisi was significantly smaller than that from PSG(S2 percentage from Quisi and PSG in normal controls was 48± 8 and 56± 9, respectively.t=2.48,P< 0.05),and other 12 sleep variables from Quisi and PSG were insignificantly different.No significant changes were found in other 12 sleep variables of the depression group,other than S1 percentage from Quisi which was significantly smaller than that from PSG(S1 percentage from Quisi and PSG in the depressed patients was 11± 4 and 13± 3,respectively.(t = 2.0,P< 0.05). Conclusion Compared with PSG, Quisi has the similar efficacy in evaluation of depression and may be easily applicable to psychological counseling,out-diagnosing and family-ward, but not to evaluate episodic diseases.