宣肺健脾益肾针刺法对支气管哮喘患者心率变异性及肺功能的影响

目的 探讨宣肺健脾益肾针刺法治疗支气管哮喘（简称哮喘）作用机理。方法 71例慢性持续期、缓解期哮喘患者，采用分层随机法分组，治疗组40例，对照组31例，两组均继续应用抗哮喘药物，治疗组同时给予针刺治疗，取宣肺健脾益肾穴位：曲池、列缺、鱼际、内关、足三里、三阴交、太溪，以平补平泻法，观察针刺治疗前后心率变异性（heart rate variability，HRV）频域指标与肺功能变化，及部分患者（17例）首次针刺治疗前后的即刻效应。结果 治疗组治疗后哮喘患者肺功能指标出现明显增高，HRV测定表明机体植物神经功能失调得到改善（P〈0．05或P〈0．01），且优于对照组治疗后（P〈0．05或P〈0．01）。结论 针刺治疗可显著提高哮喘患者的肺功能，其作用机理可能与对植物神经功能的调节作用有关。

Effects of Acupuncture for Dispersing Fei, Invigorating Pi and Reinforcing Shen on Heart Rate Variability and Pulmonary Function in Bronchial Asthma Patients

ObjectiveTo explore the acting mechanism of acupuncture treatment for dispersing Fei, invigorating Pi and reinforcing Shen (DFIPRS) on bronchial asthma. MethodsSeventy-one chronic asthma patients in persistent or remission period were randomly assigned to two groups with stratified method, the treated group (40 cases) and the control group (31 cases). Anti-asthmatic medicine were given to both groups and acupuncture therapy to the treated group additionally on the acupoints for DFIPRS including Quchi (Lt11), Lieque (LU7), Yuji (Lu10), Neiguan (P6), Zusanli (ST36), Sanyinjiao (Sp6) and Taixi (K13) using uniform reinforcing-reducing manipulation. The changes of heart rate variability (HRV) frequency-domain index and the pulmonary function were observed before and after treatment, and the immediate effect before and after the first needling of acupuncture was also observed in 17 patients. ResultsAfter acupuncture treatment, the indices of pulmonary function improved significantly and the function of vegetative nervous system, showed by HRV, were also elevated in the treated group (P<0.05 or P<0.01) and significantly superior to that in the control group after treatment (P<0.05 or P<0.01). ConclusionAcupuncture therapy could significantly improve pulmonary function of asthma patients, its mechanism may be related to the regulation of vegetative nerve function.