氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床研究

目的探究氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床疗效。方法选取本院2013年2月—2014年2月收治的高血压合并冠心病患者110例,随机分为甲、乙两组,各55例。甲组患者采用氨氯地平阿托伐他汀钙片治疗,乙组患者采用硝苯地平治疗,比较两组患者的临床疗效。结果甲组总有效率为94.5%（52/55）,高于乙组的83.6%（46/55）,差异有统计学意义（P〈0.05）。治疗后,两组患者的TC、TG、HDL-C及LDL-C均降低,且甲组均低于乙组,差异有统计学意义（P〈0.05）。结论氨氯地平阿托伐他汀钙片治疗高血压合并冠心病效果显著,能有效改善患者的血压与心率,且耐受性好、不良反应小。

Clinical Effect of Amlodipine Atorvastatin Calcium Tablets on Hypertension and Coronary Heart Disease

Objective To explore the clinical effect of amlodipine atorvastatin calcium tablets on hypertension and coronary heart disease. Methods 110 patients with hypertension and coronary heart disease in our hospital from February 2013 to February 2014 were selected, and then they were randomly divided into A group and B group, 55 cases in each. A group was treated with amlodipine atorvastatin calcium tablets, B group was treated with nifedipine. The elinical effect between the two groups was compared. Results The total effective rate of A group was 94. 5% （52/55）, was higher than that of B group of 83.6% （46/55）, the difference was statistically significant （P 〈 0. 05 ）. After treatment, TC, TG, HDL- C and LDL -C of two groups were reduced, and those of A group were lower than B group, the difference was statistically significant （ P 〈 0. 05）. Conclusion Amlodipine atorvastatin calcium tablets has remarkable clinical effect on hypertension and coronary heart disease, which can effectively improve the patients＇blood pressure and heart rate, has better tolerance and less adverse reac- tions.